Comparison of dexamethasone with local anaesthetic versus local anaesthetic for laparoscopic port infiltration to assess effectiveness for post-operative analgesia

Md. Ariful Hoque 1, Shamima Nasrin Shadia 2 and Moazzem Hossain 3, *

1 Consultant, Anesthesiology, Feni Sadar Hospital, Bangladesh.
2 Gonoshasthaya Samaj Vittik Medical College, Dhaka, Bangladesh.
3 Institute of Allergy and Clinical Immunology of Bangladesh.
 
Research Article
International Journal of Frontline Research in Chemistry and Pharmacy, 2022, 01(01), 008–013.
Article DOI: 10.56355/ijfrcp.2022.1.1.0003
Publication history: 
Received on 02 February 2022; revised on 30 March 2022; accepted on 01 April 2022
 
Abstract: 
Early postoperative pain remains the most prevalent complaint after any surgery. Beside conventional IV analgesic medications, subcutaneous infiltration has been established as a reliable pain relief technique. Addition of dexamethasone to local anaesthetic (example: bupivacaine, lidocaine) can also be used as it has some beneficial effect than use of bupivacaine only. The objectives of this study to evaluate the duration of analgesic effects of dexamethasone with local anaesthetic as compared to local anaesthetic in post operative patient. This Randomized controlled trial study was conducted among 60 patients who underwent Laparoscopic cholecystectomy. This study was conducted from January,2019 to June,2019. All patients who underwent laparoscopic cholecystectomy surgery were selected by purposive sampling. Data were compiled, edited, analyzed. The SPSS version 23 was used for data analysis. In this study distributing the patient in demographic changes, age, sex, BMI do not show any significant change. Most Group 2 patients have long analgesia effect (NRS score more than 5), delay requirement of first rescue analgesia. NRS (Numerical Rating Scale) score in Group 2 were persistently lower than that of Group 1. This revealed that combination of Bupivacaine and Dexamethasone is quite effective in reducing postoperative port site pain in comparison to Bupivacaine (P=<0.001).
 
Keywords: 
Dexamethasone; Bupivacaine; Laparoscopic; Postoperative Pain
 
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